|
|
tauroursodeoxycholate + H2O <=> ursodeoxycholate + taurine
|
3.5.1.24
choloylglycine hydrolase
3.5.1.74
chenodeoxycholoyltaurine hydrolase
|
–
–
|
M
|
|
BRENDA:
BS140669
MetaCyc:
RXN-21345
|
|
|
|
ursodeoxycholate + NADP+ <=> 7-ketolithocholic_acid + NADPH + H+
|
1.1.1.201
7beta-hydroxysteroid dehydrogenase (NADP+)
|
–
|
M
|
|
BRENDA:
BS425840
MetaCyc:
RXN-16034
|
|
|
|
ATP + ursodeoxycholate + CoA <=> AMP + diphosphate + Ursodeoxycholoyl-CoA
|
6.2.1.7
cholate---CoA ligase
|
–
|
M
|
|
MetaCyc:
RXN-21342
|
|
|
|
UDP-glucuronate + ursodeoxycholate <=> UDP + hyodeoxycholic_acid_6-O-glucuronoside
|
2.4.1.17
glucuronosyltransferase
|
–
|
|
|
BRENDA:
BS399094
|
|
|
|
UDP-N-acetyl-D-glucosamine + ursodeoxycholate <=> UDP + 7beta-(N-acetyl-D-glucosaminyl)-ursodeoxycholate
|
2.4.1.B7
|
–
|
|
|
BRENDA:
BR49256
|
|
|
|
ursodeoxycholate + UDP-glucuronate <=> UDP + ursodeoxycholic_acid_O-glucuronide
|
2.4.1.17
glucuronosyltransferase
|
–
|
|
|
BRENDA:
BS322204
|
|
|
|
ursodeoxycholate + NAD+ <=> 7-ketolithocholic_acid + NADH + H+
|
1.1.1.159
7alpha-hydroxysteroid dehydrogenase
|
–
|
|
|
BRENDA:
BS439973
|
|
|
|
ursodeoxycholate + NAD+ <=> 7alpha,12alpha-dihydroxy-5beta-cholan-3-one-24-oic_acid + NADH
|
1.1.1.50
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
|
–
|
|
|
BRENDA:
BS374888
|
|
|
|
ursodeoxycholate + NAD+ <=> 7beta-Hydroxy-3-keto-5beta-cholanoic_acid + NADH
|
1.1.1.50
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
|
–
|
|
|
BRENDA:
BS257228
|
|
|
|
lithocholic_acid + NADPH + H+ <=> ursodeoxycholate + NADP+
|
1.1.1.159
7alpha-hydroxysteroid dehydrogenase
1.1.1.201
7beta-hydroxysteroid dehydrogenase (NADP+)
|
–
–
|
|
|
BRENDA:
BS438390
|
|
|
|
chenodeoxycholic_acid + NADPH + H+ <=> ursodeoxycholate + NADP+
|
1.1.1.201
7beta-hydroxysteroid dehydrogenase (NADP+)
|
–
|
|
|
BRENDA:
BS438281
|
|
|
|
UDP-glucose + ursodeoxycholate <=> UDP + 7beta-D-glucosyl-ursodeoxycholate
|
2.4.1.B7
|
–
|
|
|
BRENDA:
BS424197
|
|
|
|
3''-phosphoadenylyl-sulfate + ursodeoxycholate <=> adenosine_3'',5''-bisphosphate + ursodeoxycholate_sulfate
|
2.8.2.14
bile-salt sulfotransferase
|
–
|
|
|
BRENDA:
BS360189
|
|
|
|
3alpha,7beta-dihydroxy-5beta-cholanoyl_glycine + H2O <=> glycine + ursodeoxycholate
|
3.5.1.24
choloylglycine hydrolase
|
–
|
|
|
BRENDA:
BS384823
|
|
|
|
glycoursodeoxycholic_acid + H2O <=> ursodeoxycholate + glycine
|
3.5.1.24
choloylglycine hydrolase
|
–
|
|
|
BRENDA:
BS448658
|
|